What Is Medication-Assisted Treatment (MAT) and How Does It Work?

Samantha Rush, APRN, FNP-C

Medical Director of Residential & Withdrawal Services

Samantha Rush is a compassionate and committed healthcare professional with a strong dedication to serving individuals on their journey to wellness and recovery. As a Family Nurse Practitioner with advanced training and clinical expertise, Samantha brings more than a decade of experience in emergency medicine, behavioral health, and substance use treatment to her role as Medical Director of Residential & Withdrawal Services.

She began her academic journey at Neosho County Community College and Ottawa University, where she was honored with induction into Phi Theta Kappa for academic excellence. She earned her Master of Science in Nursing from Rockhurst University, becoming a board-certified Family Nurse Practitioner. Driven by a commitment to continuous growth and service, Samantha is currently pursuing additional certifications as a Psychiatric-Mental Health Nurse Practitioner and a master’s degree in medical Spanish.

Samantha has served in community mental health and detox programs for the past two years, where she has been recognized for her holistic, person-centered approach to care. Prior to this, she served as an emergency department charge nurse for ten years, bringing leadership and critical care expertise to fast-paced clinical environments. In 2024, Samantha was honored as one of the top five finalists for Best of Lawrence and has been nominated again for 2025, a reflection of her outstanding reputation and dedication to the community.

Outside of her professional life, Samantha is a proud wife and mother to five children and one stepson. She is actively involved in her family’s life as a dedicated cheer mom, baseball mom, and soccer mom—roles she embraces with the same passion and energy she brings to her clinical work.

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At Avalon Wellness & Recovery, we know that addiction doesn’t exist in isolation. It affects the body, the mind, and the spirit—and successful treatment must meet people at each of those levels. That’s where Medication-Assisted Treatment (MAT) comes in. But what is Medication-Assisted Treatment (MAT) and how does it work? It’s more than just a clinical protocol. MAT is a compassionate, evidence-based approach that combines medication with therapy to support people in reclaiming their lives from the grip of opioid addiction. And for many, it’s a lifeline.

A Whole-Person Approach to Addiction Recovery

At its core, MAT is about restoring balance—both in the brain and in a person’s daily life—as part of Avalon’s broader holistic approach to healing from substance use disorders. The process begins with FDA-approved medications that reduce withdrawal symptoms and cravings. These medications stabilize the brain’s chemistry, making it easier for someone to engage in counseling, rebuild routines, and start to envision a life beyond survival.

Contrary to outdated myths, MAT is not “trading one drug for another.” Instead, it uses carefully managed medications to interrupt the chaos of addiction and open up space for healing. These medications don’t get people high. They help them feel normal.

The second component of MAT—therapy—is just as vital. Counseling provides tools to address trauma, build healthy coping mechanisms, and navigate the emotional terrain that often underlies substance use. Together, medication and therapy create a structured, supported environment where real change becomes possible.

How It Works in Real Life

When someone begins MAT, they first meet with a medical provider to determine the best medication for their needs. That might be buprenorphine, which is commonly prescribed in outpatient settings, or methadone, which is typically dispensed through specialized clinics. Some people are better suited for naltrexone, a non-opioid option that blocks the effects of opioids altogether.

The right choice depends on the person—their history, health, risk factors, and recovery goals. Once stabilized, they’ll usually begin working with a therapist and recovery team to build out the behavioral health side of the plan.

For some, MAT is a short-term bridge to stability. For others, it’s a long-term or even lifelong part of managing opioid use disorder. There’s no universal timeline. What matters is whether the treatment is working—and whether the person is safe, supported, and steadily healing.

Buprenorphine: A Key Part of the MAT Toolbox

In our recent post, we shared a deep dive into the benefits of buprenorphine. As one of the most accessible and effective medications in the MAT toolkit, buprenorphine plays a central role in helping people manage opioid addiction.

What makes it different is how it works in the brain. It activates the same receptors as opioids like heroin or oxycodone—but only partially. That means it eases withdrawal and cravings without triggering the same euphoric high. It also has what’s known as a “ceiling effect,” which dramatically reduces the risk of overdose.

Buprenorphine can be prescribed in regular doctor’s offices and taken at home. It comes in daily tablets or films, monthly injections, and even longer-term implants. This flexibility allows people to incorporate treatment into their lives without constant clinic visits.

And because buprenorphine helps people feel stable—not high, not sick—it frees them up to focus on what really matters: therapy, relationships, meaningful work, and long-term goals.

Why MAT Works—And Why It’s Saving Lives

Study after study has confirmed what we’ve seen firsthand at Avalon: MAT saves lives. It keeps people in treatment longer, dramatically reduces the risk of overdose, and improves overall quality of life.

When people aren’t consumed by withdrawal or cravings, they can hold down jobs, show up for their families, attend therapy consistently, and regain control over their future. It also has powerful ripple effects. MAT has been shown to reduce criminal justice involvement, lower the risk of contracting diseases like HIV and hepatitis C, and improve outcomes for pregnant women with opioid use disorder.

This isn’t hypothetical. It’s happening every day in clinics and treatment centers across the country—including here in Kansas.

Expanding Access in Kansas

While MAT is increasingly seen as the standard of care, it’s not equally accessible everywhere. In Kansas, access has historically been limited—especially in rural counties where people may have to drive hours just to find a prescriber.

But that’s changing.

With support from federal grants, including over $35 million in State Opioid Response (SOR) funding, and new laws like the Kansas Fights Addiction Act, the state is investing in expanding MAT programs. The recent removal of the federal “X-waiver” means more doctors than ever can now prescribe buprenorphine, further increasing access to life-saving care.

At Avalon, we’re proud to be part of this movement. We offer medication-assisted treatment right here in Lawrence, combining clinical excellence with personalized, dignity-centered support. Whether you’re coming from down the street or across the state, we’re here to meet you where you are—and help you find your way forward.

There’s No One Right Way—Only the Way That Works for You

Medication-Assisted Treatment isn’t for everyone, but for many, it’s the difference between surviving and thriving. It’s not a shortcut. It’s not giving up. It’s choosing a path that’s grounded in science, compassion, and a deep belief that recovery is possible—and worth fighting for.

If you or someone you love is struggling with opioid addiction, MAT may be the right next step. And if you’re not sure yet, that’s okay. Reach out. Ask questions. We’ll walk with you at your pace, with no judgment.

Ready to Learn More?

Call Avalon Wellness & Recovery today to talk with a member of our team. We’ll help you understand your options and find the treatment path that makes sense for your story—including MAT with buprenorphine if that’s the right fit.

Because the goal isn’t just to stop using. The goal is to start living.

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